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Clinical trials in Leiden – page 22

401 clinical trials in Leiden, The Netherlands across 4 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

The NetherlandsOur site in the NetherlandsKlinischOnderzoek.nl(opens in a new tab)
Leiden at a glance
401
clinical trials
  • Research sites4
Type of trial
Recruitment status
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401 trials in Leiden

Open in trial search

Drug use disorder

Not recruiting

Study on Reversing Opioid-Induced Breathing Problems Using Naloxone and Nalmefene in Healthy Volunteers and Opioid Users

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Fentanyl Citrate
  • Sponsor:Leids Universitair Medisch Centrum (LUMC)

Study on the Effect of Fentanyl and Naloxone on Breathing Patterns in Healthy Individuals

Not recruiting
Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · Healthy volunteers
  • Substances:Fentanyl Citrate
  • Sponsor:Leids Universitair Medisch Centrum (LUMC)

Nervous system disorder

Not recruiting

Study on the Effects of Cannabidiol on the Central Nervous System in Healthy Male Participants

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · Healthy volunteers
  • Substances:Cannabidiol
  • Sponsor:Centre for Human Drug Research

Rhinovirus infection

Not recruiting

Study on 2-Deoxy-D-Glucose for Preventing Common Cold in Healthy Adults

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · Healthy volunteers
  • Substances:2-DEOXY-D-GLUCOSE
  • Sponsor:G.ST Antivirals GmbH

Spinal muscular atrophy

Not recruiting

Study on the Safety and Tolerability of BIIB115 for Children with Spinal Muscular Atrophy Previously Treated with Gene Therapy

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:0–17 years · 18–64 years · Healthy volunteers
  • Substances:BIIB115
  • Sponsor:Biogen Idec Research Limited

Pain

Not recruiting

Study on the Effects of Tetrodotoxin for Pain Relief in Healthy Volunteers

InvestigationalNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · Healthy volunteers
  • Substances:TETRODOTOXIN
  • Sponsor:Leids Universitair Medisch Centrum (LUMC)

Study on Sofosbuvir for Preventing Yellow Fever in Healthy Volunteers

Not recruiting
Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · Healthy volunteers
  • Substances:SOFOSBUVIR
  • Sponsor:Leids Universitair Medisch Centrum (LUMC)

Study on the Effects of Acetylcysteine and Naloxone on Opioid-Induced Breathing Problems in Healthy Individuals

Not recruiting
Registered drug
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · Healthy volunteers
  • Substances:Acetylcysteine
  • Sponsor:Leids Universitair Medisch Centrum (LUMC)

Liver transplant+2

Not recruiting

Study on How Pantoprazole Affects the Absorption of Mycophenolate Mofetil in Post-Transplant Patients

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · Healthy volunteers
  • Substances:Pantoprazole
  • Sponsor:Leids Universitair Medisch Centrum (LUMC)

Chronic graft versus host disease

Not recruiting

Study Comparing Axatilimab to Best Available Therapy for Patients with Chronic Graft-Versus-Host Disease After Two or More Treatments

InvestigationalNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Axatilimab
  • Sponsor:Incyte Corp.

Cerebral amyloid angiopathy

Not recruiting

Study on the Safety and Effects of ALN-APP for Patients with Cerebral Amyloid Angiopathy

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:ALN-961583
  • Sponsor:Alnylam Pharmaceuticals Inc.

Ocular myasthenia

Not recruiting

Study on the Effectiveness and Safety of Efgartigimod in Adults with Ocular Myasthenia Gravis

Registered drug
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Efgartigimod Alfa
  • Sponsor:Argenx

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Clinical research in Leiden

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01 Infectious Diseases Research

Innovative studies focusing on viral infections including trials evaluating vaccines against yellow fever, influenza, and mpox. Research includes assessment of antibody responses and vaccine effectiveness in different populations.

  • Influenza vaccine efficacy in elderly
  • Yellow fever prophylaxis
  • Mpox booster vaccination

Particular emphasis on preventive strategies and immune response evaluation.

02 Neurological Studies

Comprehensive research targeting neurological conditions, including investigations into Parkinson's disease treatments and neural response patterns. Studies examine innovative therapeutic approaches.

  • Parkinson's Disease treatments
  • CNS response analysis
  • Cerebral Amyloid Angiopathy

Focus on developing targeted therapies and understanding brain mechanisms.

03 Cancer and Chronic Conditions

Advanced research in oncology and chronic diseases, including studies on gastric cancer imaging and T-cell lymphoma treatments. Investigations into kidney disease management.

  • Advanced solid tumors
  • Gastric cancer diagnosis
  • Chronic kidney disease

Emphasis on innovative diagnostic techniques and treatment approaches.

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