Clinical trials in Nijmegen – page 15

579 clinical trials in Nijmegen, The Netherlands across 7 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Nijmegen at a glance

579

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579 trials in Nijmegen

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Duchenne muscular dystrophy

Recruiting

Long-Term Safety and Efficacy Study of Givinostat for Patients with Duchenne Muscular Dystrophy Previously Treated with Givinostat

InvestigationalNo placebo

Long-Term Safety and Efficacy Study of Givinostat for Patients with Duchenne Muscular Dystrophy Previously Treated with Givinostat

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Givinostat
Sponsor:Italfarmaco S.p.A.

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HER2 gene amplification

Recruiting

Study of zongertinib tablets in patients with advanced solid tumors that have HER2 gene changes

InvestigationalNo placebo

Study of zongertinib tablets in patients with advanced solid tumors that have HER2 gene changes

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Zongertinib
Sponsor:Boehringer Ingelheim Espana S.A.

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Pain+1

Recruiting

Comparing Buprenorphine/Naloxone and Methadone for Opioid Use Disorder in Patients with Chronic Pain: A Study on Reducing Opioid Misuse

Registered drugNo placebo

Comparing Buprenorphine/Naloxone and Methadone for Opioid Use Disorder in Patients with Chronic Pain: A Study on Reducing Opioid Misuse

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Buprenorphine
Sponsor:Stichting Radboud University Medical Center

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Acute myocardial infarction

Recruiting

Study on the Safety of Ticagrelor and Aspirin in Patients with ST-Elevation Myocardial Infarction After Heart Procedure

Registered drugNo placebo

Study on the Safety of Ticagrelor and Aspirin in Patients with ST-Elevation Myocardial Infarction After Heart Procedure

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Acetylsalicylic Acid
Sponsor:Stichting Radboud University Medical Center

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Subdural haematoma

Recruiting

Study on Tranexamic Acid to Prevent Surgery in Patients with Chronic Subdural Hematoma

Registered drug

Study on Tranexamic Acid to Prevent Surgery in Patients with Chronic Subdural Hematoma

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Tranexamic Acid
Sponsor:Amsterdam UMC Stichting

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Foetal exposure during pregnancy+2

Recruiting

Study of Metformin to Extend Pregnancy Duration in Women with Preterm Preeclampsia

Registered drug

Study of Metformin to Extend Pregnancy Duration in Women with Preterm Preeclampsia

Registered drug

The Netherlands

Participants:18–64 years
Substances:Metformin Hydrochloride
Sponsor:Amsterdam UMC Stichting

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Paraganglion neoplasm

Recruiting

Study on Using Exenatide PET/CT Imaging for Detecting Paragangliomas in Patients

Registered drugNo placebo

Study on Using Exenatide PET/CT Imaging for Detecting Paragangliomas in Patients

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Exenatide
Sponsor:Stichting Radboud University Medical Center

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Neoplasm malignant

Recruiting

Study of Lower Dose Olaparib Combined with Cobicistat to Improve Treatment Tolerance in Cancer Patients

Registered drugNo placebo

Study of Lower Dose Olaparib Combined with Cobicistat to Improve Treatment Tolerance in Cancer Patients

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Cobicistat
Sponsor:Stichting Radboud University Medical Center

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Rectal cancer

Recruiting

Evaluating SGM-101 (fluorochrome-labeled antibody) in patients with locally advanced or recurrent rectal cancer undergoing surgery

InvestigationalNo placebo

Evaluating SGM-101 (fluorochrome-labeled antibody) in patients with locally advanced or recurrent rectal cancer undergoing surgery

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Chimeric Monoclonal Antibody Against Carcinoembryonic Antigen Conjugated To Fluorochrome Bm-104
Sponsor:Leids Universitair Medisch Centrum (LUMC)

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Non-small cell lung cancer

Recruiting

Study of Adagrasib Alone and with Pembrolizumab for Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation

Registered drugNo placebo

Study of Adagrasib Alone and with Pembrolizumab for Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Adagrasib
Sponsor:Mirati Therapeutics Inc.

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Haemolytic uraemic syndrome

Recruiting

Study on the Effectiveness of INM004 for Children with Hemolytic Uremic Syndrome Caused by Shiga Toxin-Producing E. coli

Investigational

Study on the Effectiveness of INM004 for Children with Hemolytic Uremic Syndrome Caused by Shiga Toxin-Producing E. coli

Investigational

The Netherlands

Participants:0–17 years
Substances:Equine Immunoglobulin F(Ab')2 Fragments Targeting Shiga Toxin
Sponsor:Chemo Research S.L.

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Oesophageal adenocarcinoma

Recruiting

Study on Adding Trastuzumab and Pertuzumab to Treatment for Patients with Resectable HER2 Positive Esophageal Cancer

Registered drugNo placebo

Study on Adding Trastuzumab and Pertuzumab to Treatment for Patients with Resectable HER2 Positive Esophageal Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Pertuzumab
Sponsor:Amsterdam UMC Stichting

Contact Research Centre

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Clinical research in Nijmegen

What the registry says about research in the country

01 Neurological Studies

Research focusing on various brain conditions, including glioblastoma imaging techniques and treatments for status epilepticus. Studies investigate brain tissue infiltration patterns and post-cardiac arrest neural conditions.

Brain tumor visualization
Serotonin's role in decision-making
Post-trauma stress disorders

Advanced imaging techniques and therapeutic interventions are being evaluated to improve patient outcomes.

02 Cardiovascular Research

Comprehensive studies examining heart failure prevention and treatment approaches. Investigations include new drug combinations and preventive strategies for cardiovascular events.

Heart failure prevention
Cardiovascular disease management
Post-cardiac arrest care

Clinical trials focus on both preventive measures and acute treatment protocols.

03 Cancer Studies

Innovative research in oncology, particularly focusing on advanced treatment approaches for various cancer types, including breast cancer and leukemia.

Breast cancer imaging
Leukemia treatments
Gastric cancer therapies

Studies evaluate new therapeutic combinations and diagnostic techniques.

04 Metabolic Disorders

Research examining gestational diabetes and obesity treatments, with emphasis on innovative imaging techniques and therapeutic approaches.

Diabetes management
Obesity treatments
Metabolic imaging

Focus on developing personalized treatment strategies.

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