Clinical trials in Sofia – page 31

763 clinical trials in Sofia, Bulgaria across 17 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

Sofia at a glance

763

clinical trials

Research sites17

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763 trials in Sofia

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Dermatitis atopic

Not recruiting

Study on the Long-Term Safety and Efficacy of Nemolizumab for Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis

InvestigationalNo placebo

Study on the Long-Term Safety and Efficacy of Nemolizumab for Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis

InvestigationalNo placebo

Bulgaria

Participants:0–17 years · 18–64 years · 65+ years
Substances:Nemolizumab
Sponsor:Galderma S.A.

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Hidradenitis

Not recruiting

Study on the Effects of Sonelokimab for Adults with Moderate to Severe Hidradenitis Suppurativa

Investigational

Study on the Effects of Sonelokimab for Adults with Moderate to Severe Hidradenitis Suppurativa

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Sonelokimab
Sponsor:MoonLake Immunotherapeutics AG

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Hypertriglyceridaemia

Not recruiting

Study of Plozasiran for Adults with Severe Hypertriglyceridemia

Investigational

Study of Plozasiran for Adults with Severe Hypertriglyceridemia

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Synthetic Double-Stranded Sirna Oligonucleotide Directed Against Apolipoprotein C-Iii Mrna And Covalently Linked To A Ligand Containing Three N-Acetylgalactosamine Residues
Sponsor:Arrowhead Pharmaceuticals Inc.

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Colitis ulcerative+1

Not recruiting

Study on the Long-Term Effects of TEV-48574 (Duvakitug) for Adults with Moderate to Severe Ulcerative Colitis or Crohn's Disease

InvestigationalNo placebo

Study on the Long-Term Effects of TEV-48574 (Duvakitug) for Adults with Moderate to Severe Ulcerative Colitis or Crohn's Disease

InvestigationalNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Duvakitug
Sponsor:Teva Branded Pharmaceutical Products R&D LLC

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Osteoporosis

Not recruiting

Study Comparing MAB-22 and Denosumab for Treating Osteoporosis in Postmenopausal Women

Registered drugNo placebo

Study Comparing MAB-22 and Denosumab for Treating Osteoporosis in Postmenopausal Women

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Denosumab
Sponsor:Xentria Inc.

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Ovarian cancer

Not recruiting

Study on the Effectiveness of Durvalumab, Olaparib, and Bevacizumab in Patients with Newly Diagnosed Advanced Ovarian Cancer

Registered drug

Study on the Effectiveness of Durvalumab, Olaparib, and Bevacizumab in Patients with Newly Diagnosed Advanced Ovarian Cancer

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Bevacizumab
Sponsor:AstraZeneca AB

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Hypertriglyceridaemia

Not recruiting

Study to Evaluate Plozasiran for Adults with High Triglycerides

Investigational

Study to Evaluate Plozasiran for Adults with High Triglycerides

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Synthetic Double-Stranded Sirna Oligonucleotide Directed Against Apolipoprotein C-Iii Mrna And Covalently Linked To A Ligand Containing Three N-Acetylgalactosamine Residues
Sponsor:Arrowhead Pharmaceuticals Inc.

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Systemic lupus erythematosus

Not recruiting

Study of Obexelimab Treatment for Adults with Systemic Lupus Erythematosus (SLE)

Registered drug

Study of Obexelimab Treatment for Adults with Systemic Lupus Erythematosus (SLE)

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Obexelimab
Sponsor:Zenas Biopharma (USA) LLC

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Chronic spontaneous urticaria

Not recruiting

Study on Barzolvolimab for Patients with Chronic Spontaneous Urticaria Unresponsive to H1 Antihistamines

Registered drug

Study on Barzolvolimab for Patients with Chronic Spontaneous Urticaria Unresponsive to H1 Antihistamines

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Barzolvolimab
Sponsor:Celldex Therapeutics Inc.

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Study on the Effectiveness and Safety of LY06006 and Denosumab for Postmenopausal Women with Osteoporosis

Not recruiting

Registered drugNo placebo

Study on the Effectiveness and Safety of LY06006 and Denosumab for Postmenopausal Women with Osteoporosis

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Denosumab
Sponsor:Shandong Boan Biotechnology Co. Ltd.

Contact Research Centre

Rheumatoid arthritis

Not recruiting

Study on the Effects of AP1189 and Methotrexate for Patients with Early Rheumatoid Arthritis and Active Inflammation

Registered drug

Study on the Effects of AP1189 and Methotrexate for Patients with Early Rheumatoid Arthritis and Active Inflammation

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Methotrexate
Sponsor:Synact Pharma ApS

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Chronic spontaneous urticaria

Not recruiting

Study on Barzolvolimab for Patients with Chronic Spontaneous Urticaria Unresponsive to H1 Antihistamines

Registered drug

Study on Barzolvolimab for Patients with Chronic Spontaneous Urticaria Unresponsive to H1 Antihistamines

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Barzolvolimab
Sponsor:Celldex Therapeutics Inc.

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Clinical research in Sofia

What the registry says about research in the country

01 Respiratory Research

Clinical studies focusing on respiratory infections and conditions, including trials for RSV, human metapneumovirus, and influenza vaccines in older adults. Research also includes investigations into asthma treatments and chronic rhinosinusitis management.

Respiratory Syncytial Virus (RSV)
Influenza Prevention
Chronic Rhinosinusitis
Asthma Management

02 Dermatological Studies

Comprehensive research into various skin conditions, evaluating new treatments for chronic urticaria, hidradenitis suppurativa, and different forms of psoriasis. These trials aim to improve patient outcomes through innovative therapeutic approaches.

Chronic Spontaneous Urticaria
Hidradenitis Suppurativa
Genital Psoriasis
Plaque Psoriasis

03 Autoimmune Disorders

Groundbreaking studies examining treatments for various autoimmune conditions, including multiple sclerosis, Sjögren's disease, and systemic sclerosis. Research focuses on developing targeted therapies to manage these chronic conditions.

Multiple Sclerosis
Sjögren's Disease
Systemic Sclerosis
Psoriatic Arthritis

04 Metabolic and Cardiovascular Research

Studies investigating treatments for metabolic disorders and heart conditions, including research on hypertriglyceridemia, obesity management, and heart failure prevention. Focus on both therapeutic interventions and preventive measures.

Hypertriglyceridemia
Obesity Management
Heart Failure Prevention
Cardiovascular Health

05 Oncology Research

Advanced clinical trials focusing on breast cancer treatments and blood disorders, particularly investigating new therapeutic approaches for advanced/metastatic breast cancer and myelodysplastic syndrome.

Advanced Breast Cancer
Myelodysplastic Syndrome
Targeted Therapies

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Clinical trials in Sofia – page 31

763 trials in Sofia

Dermatitis atopic

Study on the Long-Term Safety and Efficacy of Nemolizumab for Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis

Hidradenitis

Study on the Effects of Sonelokimab for Adults with Moderate to Severe Hidradenitis Suppurativa

Hypertriglyceridaemia

Study of Plozasiran for Adults with Severe Hypertriglyceridemia

Colitis ulcerative+1

Study on the Long-Term Effects of TEV-48574 (Duvakitug) for Adults with Moderate to Severe Ulcerative Colitis or Crohn's Disease

Osteoporosis

Study Comparing MAB-22 and Denosumab for Treating Osteoporosis in Postmenopausal Women

Ovarian cancer

Study on the Effectiveness of Durvalumab, Olaparib, and Bevacizumab in Patients with Newly Diagnosed Advanced Ovarian Cancer

Hypertriglyceridaemia

Study to Evaluate Plozasiran for Adults with High Triglycerides

Systemic lupus erythematosus

Study of Obexelimab Treatment for Adults with Systemic Lupus Erythematosus (SLE)

Chronic spontaneous urticaria

Study on Barzolvolimab for Patients with Chronic Spontaneous Urticaria Unresponsive to H1 Antihistamines

Study on the Effectiveness and Safety of LY06006 and Denosumab for Postmenopausal Women with Osteoporosis

Study on the Effectiveness and Safety of LY06006 and Denosumab for Postmenopausal Women with Osteoporosis

Rheumatoid arthritis

Study on the Effects of AP1189 and Methotrexate for Patients with Early Rheumatoid Arthritis and Active Inflammation

Chronic spontaneous urticaria

Study on Barzolvolimab for Patients with Chronic Spontaneous Urticaria Unresponsive to H1 Antihistamines

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Clinical trials in Sofia – page 31

763 trials in Sofia

Colitis ulcerative+1

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Clinical research in Sofia

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