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Clinical trials in Sofia – page 52

763 clinical trials in Sofia, Bulgaria across 17 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

Sofia at a glance
763
clinical trials
  • Research sites17
Type of trial
Recruitment status
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763 trials in Sofia

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Hereditary angioedema with C1 esterase inhibitor deficiency+1

Not recruiting

Study on Oral PHA-022121 for Preventing Angioedema Attacks in Patients with Hereditary Angioedema

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:(S)-N-(1-Deutero-1-(3-Chloro-5-Fluoro-2-((2-Methyl-4-(1-Methyl-1H-1,2,4-Triazol-5-Yl)Quinolin-8-Yloxy)Methyl)Phenyl)Ethyl)-2-(Difluoromethoxy)Acetamide
  • Sponsor:Pharvaris Netherlands B.V.

Hormone receptor positive breast cancer

Not recruiting

Study of OP-1250 for Treating Advanced or Metastatic ER+, HER2- Breast Cancer in Patients After Endocrine and CDK4/6 Inhibitor Therapy

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Anastrozole
  • Sponsor:Olema Pharmaceuticals Inc.

Type 2 diabetes mellitus

Not recruiting

Study on the Effects of Switching from Daily Basal Insulin to Weekly Insulin Icodec Compared to Daily Insulin Glargine in Adults with Type 2 Diabetes

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Insulin Glargine
  • Sponsor:Novo Nordisk A/S

Long-term Safety Study of Emraclidine for Adults with Schizophrenia

Not recruiting
InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Emraclidine
  • Sponsor:Cerevel Therapeutics LLC

Cachexia

Not recruiting

Study of ponsegromab for patients with cancer cachexia and elevated GDF-15 levels

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Ponsegromab
  • Sponsor:Pfizer Inc.

Hypertension

Not recruiting

Study on Baxdrostat for Lowering Blood Pressure in Patients with Resistant Hypertension

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Baxdrostat
  • Sponsor:AstraZeneca AB

Diffuse large B-cell lymphoma

Not recruiting

Study on the Safety and Effectiveness of Epcoritamab with R-CHOP for Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Cyclophosphamide
  • Sponsor:AbbVie Deutschland GmbH & Co. KG

Colorectal cancer

Not recruiting

Study for Patients with Metastatic Colorectal Cancer with BRAF V600E Mutation Using Encorafenib, Cetuximab, and Chemotherapy Combination

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Pfizer Inc.

Chronic kidney disease

Not recruiting

Study on the Effectiveness and Safety of Finerenone for Adults with Non-Diabetic Chronic Kidney Disease

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Finerenone
  • Sponsor:Bayer AG

Bronchiectasis

Not recruiting

Study on the Safety and Tolerability of Nebulised Sodium Nitrite Formulations in Patients with Non-Cystic Fibrosis Bronchiectasis and Pseudomonas Aeruginosa

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Salbutamol Sulfate
  • Sponsor:Thirty Respiratory Limited

Psoriatic arthropathy

Not recruiting

Study on Guselkumab for Treating Active Psoriatic Arthritis in Patients with Inadequate Response to One Prior Anti-TNF Agent

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Guselkumab
  • Sponsor:Janssen Cilag International

Hereditary angioedema

Not recruiting

Study on Long-Term Safety of Donidalorsen for Patients with Hereditary Angioedema

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Donidalorsen
  • Sponsor:Ionis Pharmaceuticals Inc.

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Clinical research in Sofia

What the registry says about research in the country

01 Respiratory Research

Clinical studies focusing on respiratory infections and conditions, including trials for RSV, human metapneumovirus, and influenza vaccines in older adults. Research also includes investigations into asthma treatments and chronic rhinosinusitis management.

  • Respiratory Syncytial Virus (RSV)
  • Influenza Prevention
  • Chronic Rhinosinusitis
  • Asthma Management
02 Dermatological Studies

Comprehensive research into various skin conditions, evaluating new treatments for chronic urticaria, hidradenitis suppurativa, and different forms of psoriasis. These trials aim to improve patient outcomes through innovative therapeutic approaches.

  • Chronic Spontaneous Urticaria
  • Hidradenitis Suppurativa
  • Genital Psoriasis
  • Plaque Psoriasis
03 Autoimmune Disorders

Groundbreaking studies examining treatments for various autoimmune conditions, including multiple sclerosis, Sjögren's disease, and systemic sclerosis. Research focuses on developing targeted therapies to manage these chronic conditions.

  • Multiple Sclerosis
  • Sjögren's Disease
  • Systemic Sclerosis
  • Psoriatic Arthritis
04 Metabolic and Cardiovascular Research

Studies investigating treatments for metabolic disorders and heart conditions, including research on hypertriglyceridemia, obesity management, and heart failure prevention. Focus on both therapeutic interventions and preventive measures.

  • Hypertriglyceridemia
  • Obesity Management
  • Heart Failure Prevention
  • Cardiovascular Health
05 Oncology Research

Advanced clinical trials focusing on breast cancer treatments and blood disorders, particularly investigating new therapeutic approaches for advanced/metastatic breast cancer and myelodysplastic syndrome.

  • Advanced Breast Cancer
  • Myelodysplastic Syndrome
  • Targeted Therapies
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