Clinical trials in Zwolle – page 7

197 clinical trials in Zwolle, The Netherlands across 4 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Zwolle at a glance

197

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197 trials in Zwolle

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Prolymphocytic leukaemia+2

Recruiting

Study on the Effectiveness of Entrectinib and Other Drug Combinations for Patients with Advanced Solid Tumors, Multiple Myeloma, or Non-Hodgkin Lymphoma

Registered drugNo placebo

Study on the Effectiveness of Entrectinib and Other Drug Combinations for Patients with Advanced Solid Tumors, Multiple Myeloma, or Non-Hodgkin Lymphoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Abemaciclib
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Renal cell carcinoma

Recruiting

Study on Cabozantinib and Drug Combination for Untreated Metastatic Renal Cell Carcinoma in Intermediate and Poor Risk Patients

Registered drugNo placebo

Study on Cabozantinib and Drug Combination for Untreated Metastatic Renal Cell Carcinoma in Intermediate and Poor Risk Patients

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Axitinib
Sponsor:Institut Gustave Roussy

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Rectal cancer recurrent

Recruiting

Study Comparing Chemotherapy with Irinotecan, Folinic Acid, and Oxaliplatin for Patients with Locally Recurrent Rectal Cancer

Registered drugNo placebo

Study Comparing Chemotherapy with Irinotecan, Folinic Acid, and Oxaliplatin for Patients with Locally Recurrent Rectal Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Capecitabine
Sponsor:Catharina Ziekenhuis Stichting

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Diffuse large B-cell lymphoma

Recruiting

Study on Preventing Heart Problems in Patients with Diffuse Large B-Cell Lymphoma Using Dexrazoxane and a Drug Combination

Registered drugNo placebo

Study on Preventing Heart Problems in Patients with Diffuse Large B-Cell Lymphoma Using Dexrazoxane and a Drug Combination

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Cyclophosphamide
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

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Hormone receptor positive breast cancer

Recruiting

Study Comparing MK-2870 and Pembrolizumab with Chemotherapy for Patients with Advanced Hormone Receptor Positive Breast Cancer

Registered drugNo placebo

Study Comparing MK-2870 and Pembrolizumab with Chemotherapy for Patients with Advanced Hormone Receptor Positive Breast Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Capecitabine
Sponsor:Merck Sharp & Dohme LLC

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Colorectal cancer metastatic

Recruiting

Dose-Reduced Oxaliplatin and Drug Combination Study for Older Patients with Metastatic Colorectal Cancer

Registered drugNo placebo

Dose-Reduced Oxaliplatin and Drug Combination Study for Older Patients with Metastatic Colorectal Cancer

Registered drugNo placebo

The Netherlands

Participants:65+ years
Substances:Capecitabine
Sponsor:Leids Universitair Medisch Centrum (LUMC)

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Crohn's disease

Recruiting

Study on Infliximab for Children with Crohn's Disease

Registered drugNo placebo

Study on Infliximab for Children with Crohn's Disease

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Infliximab
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Non-small cell lung cancer

Recruiting

Study of MK-1084 and Pembrolizumab for First-Line Treatment in Patients with Metastatic Non-Small Cell Lung Cancer with KRAS G12C Mutation and High PD-L1 Levels

Registered drug

Study of MK-1084 and Pembrolizumab for First-Line Treatment in Patients with Metastatic Non-Small Cell Lung Cancer with KRAS G12C Mutation and High PD-L1 Levels

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Mk-1084
Sponsor:Merck Sharp & Dohme LLC

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Disease risk factor

Recruiting

Study on Rosuvastatin and Placebo for Patients with Statin Intolerance and High Cardiovascular Risk

Investigational

Study on Rosuvastatin and Placebo for Patients with Statin Intolerance and High Cardiovascular Risk

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Atorvastatin Calcium
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Colorectal cancer metastatic+2

Recruiting

Study on the Effectiveness of Floxuridine and Drug Combination for Patients with Unresectable Colorectal Liver Metastases

Registered drugNo placebo

Study on the Effectiveness of Floxuridine and Drug Combination for Patients with Unresectable Colorectal Liver Metastases

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Bevacizumab
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Pancreatic carcinoma

Recruiting

Study of personalized FOLFIRINOX drug combination dosing (fluorouracil, irinotecan, oxaliplatin, and calcium folinate) for patients with pancreatic cancer

Registered drugNo placebo

Study of personalized FOLFIRINOX drug combination dosing (fluorouracil, irinotecan, oxaliplatin, and calcium folinate) for patients with pancreatic cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Calcium Folinate
Sponsor:Catharina Ziekenhuis Stichting

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Habitual abortion

Recruiting

Study on Prednisolone for Women with Unexplained Recurrent Miscarriages

Registered drug

Study on Prednisolone for Women with Unexplained Recurrent Miscarriages

Registered drug

The Netherlands

Participants:18–64 years
Substances:Prednisolone
Sponsor:Leids Universitair Medisch Centrum (LUMC)

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Clinical research in Zwolle

What the registry says about research in the country

01 Oncology Research

Innovative clinical trials exploring treatments for colorectal cancer, non-small cell lung cancer, and acute myeloid leukemia. Studies focus on evaluating novel drug combinations and targeted therapies to improve patient outcomes.

Advanced cancer treatments
Targeted therapy combinations
Immunotherapy research

Several trials investigating new approaches for melanoma and prostate cancer management.

02 Cardiovascular Studies

Research focusing on heart failure prevention and cardiovascular disease management. Trials evaluating new drug combinations including baxdrostat and dapagliflozin for improved cardiac outcomes.

Heart failure prevention
Cardiovascular risk reduction
Novel therapeutic approaches

Emphasis on preventive strategies and innovative treatment combinations.

03 Neurological Disorders

Clinical investigations into narcolepsy and Alzheimer's disease treatments. Studies evaluating new therapeutic options for Dravet Syndrome and various neurological conditions.

Sleep disorders
Cognitive function
Seizure management

Focus on improving quality of life and symptom management for patients.

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