Primary progressive multiple sclerosis
RecruitingOrelabrutinib in Patients with Primary Progressive Multiple Sclerosis
- Disease:Primary progressive multiple sclerosis
- Substances:–
Belgium- Participants:18–64 years
- Sponsor:Zenas Biopharma (USA) LLC
Rare diseases
Investigational molecules
Locations
Clinical trials in Belgium – page 22 166 clinical trials in Belgium across 64 research sites in 170 cities. Every trial is listed in the EU Clinical Trials Register and updated daily.
Belgium
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BelgiumWhere most of the country's trials are run
Shares are of these cities' trials together.
170 cities, A–Z – pick yours to filter the trials
What the registry says about research in the country
Belgium is conducting extensive research in oncology, focusing on both solid tumors and hematologic cancers. Clinical trials investigate novel therapies for non-small cell lung cancer, breast cancer, colorectal cancer, and melanoma. Research includes testing targeted therapies, immunotherapies, and combination treatments to improve patient outcomes across various cancer stages.
Studies explore CAR-T cell therapy, checkpoint inhibitors, and novel targeted agents for patients with relapsed or refractory disease. Research also evaluates biomarker-guided treatment selection and maintenance therapies following initial response to treatment.
Significant research efforts focus on inflammatory bowel disease, including Crohn's disease and ulcerative colitis. Trials evaluate biologics and small molecules targeting specific inflammatory pathways. Studies also investigate rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus.
Research includes axial spondyloarthritis, myasthenia gravis, and vasculitis. Trials examine both induction and maintenance strategies, often comparing new agents to standard therapies or placebo in well-defined patient populations.
Belgian trials address multiple sclerosis, Alzheimer's disease, and Parkinson's disease. Studies evaluate disease-modifying therapies and symptomatic treatments. Research in epilepsy includes rare forms such as Dravet syndrome and CDKL5 deficiency disorder.
Clinical investigations include amyotrophic lateral sclerosis, frontotemporal dementia, and narcolepsy. Trials often incorporate biomarkers and advanced imaging to monitor disease progression and treatment response.
Research encompasses heart failure, atherosclerotic cardiovascular disease, and atrial fibrillation. Studies evaluate novel anticoagulants, heart failure medications, and interventions for reducing cardiovascular events. Metabolic research includes type 2 diabetes, obesity, and dyslipidemia.
Trials investigate hypertrophic cardiomyopathy, pulmonary arterial hypertension, and amyloid cardiomyopathy. Research also addresses weight management, glycemic control, and cardiovascular risk reduction in high-risk populations.
Clinical trials focus on asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis. Research evaluates biologics targeting specific inflammatory pathways and novel bronchodilators. Studies also investigate cystic fibrosis and bronchiectasis.
Research includes eosinophilic esophagitis and chronic rhinosinusitis with nasal polyps. Trials often assess exacerbation rates, lung function improvements, and quality of life measures in patients with chronic respiratory conditions.
Belgium conducts research on Duchenne muscular dystrophy, spinal muscular atrophy, and hemophilia. Studies evaluate gene therapies, enzyme replacement treatments, and novel approaches to managing inherited conditions. Research also addresses Fabry disease, Pompe disease, and various metabolic disorders.
Trials investigate sickle cell disease, beta-thalassemia, and primary hyperoxaluria. Research includes both pediatric and adult populations, often focusing on improving quality of life and preventing disease complications.
Clinical research addresses chronic kidney disease, IgA nephropathy, and focal segmental glomerulosclerosis. Trials evaluate therapies to slow disease progression and reduce proteinuria. Studies also investigate autosomal dominant polycystic kidney disease and kidney transplant rejection.
Research includes complement-mediated kidney diseases and Alport syndrome. Trials often incorporate renal function monitoring and assessment of cardiovascular outcomes in patients with kidney disease.
Belgium participates in trials for COVID-19, respiratory syncytial virus, and influenza. Research evaluates vaccines, antiviral therapies, and preventive strategies. Studies also address HIV infection, hepatitis B and D, and cytomegalovirus infection.
Clinical investigations include invasive fungal infections, bacterial pneumonia, and sexually transmitted infections. Research addresses both prevention and treatment, with focus on vulnerable populations including immunocompromised patients.
Dermatological research focuses on atopic dermatitis, psoriasis, and hidradenitis suppurativa. Trials evaluate biologics and small molecules targeting inflammatory pathways. Studies also investigate vitiligo, alopecia areata, and rare skin conditions.
Research includes chronic spontaneous urticaria and prurigo nodularis. Trials assess disease severity, quality of life improvements, and long-term safety of new therapeutic approaches.
Beyond inflammatory bowel disease, research addresses non-alcoholic steatohepatitis, primary biliary cholangitis, and liver cirrhosis. Studies evaluate antifibrotic agents and treatments for complications of liver disease. Research also includes eosinophilic esophagitis and functional gastrointestinal disorders.
Trials investigate hepatic encephalopathy, acute-on-chronic liver failure, and short bowel syndrome. Research often includes assessment of liver function, fibrosis progression, and patient-reported outcomes.
Clinical trials address neovascular age-related macular degeneration, geographic atrophy, and diabetic retinopathy. Research evaluates anti-VEGF therapies and novel approaches to preserving vision. Studies also investigate rare inherited retinal diseases.
Research includes Leber congenital amaurosis, retinitis pigmentosa, and Stargardt disease. Trials assess visual acuity outcomes, disease progression, and quality of life in patients with vision-threatening conditions.
Pediatric research encompasses juvenile idiopathic arthritis, pediatric inflammatory bowel disease, and childhood cancers. Studies evaluate age-appropriate formulations and dosing regimens. Research also addresses autism spectrum disorder, ADHD, and rare pediatric conditions.
Trials investigate growth disorders, congenital heart disease, and bronchopulmonary dysplasia. Research often includes long-term safety monitoring and assessment of developmental outcomes in pediatric populations.
Research addresses chronic pain, neuropathic pain, and migraine. Studies evaluate novel analgesics and preventive treatments. Clinical trials also investigate anesthetic techniques and perioperative pain management strategies.
Trials include studies on fibromyalgia, chronic cough, and post-surgical pain. Research evaluates both pharmacological and interventional approaches to pain management across various clinical settings.
Clinical trials focus on major depressive disorder, schizophrenia, and post-traumatic stress disorder. Research evaluates novel antidepressants, antipsychotics, and adjunctive therapies. Studies also investigate bipolar disorder and treatment-resistant depression.
Research includes Alzheimer's disease-related psychosis and substance use disorders. Trials assess symptom improvement, functional outcomes, and long-term safety of psychiatric medications.
Research addresses solid organ transplantation, hematopoietic stem cell transplantation, and graft-versus-host disease. Studies evaluate immunosuppressive regimens and strategies to prevent rejection. Clinical trials also investigate regenerative approaches for tissue repair.
Trials include research on kidney transplantation, liver transplantation, and complications following transplantation. Studies often focus on improving long-term outcomes and reducing immunosuppression-related complications.
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