Crohn's disease
Not recruitingStudy of AZD7798 compared to placebo in patients with moderate to severe Crohn's disease
- Disease:Crohn's disease
- Substances:Azd7798
Germany- Participants:18–64 years · 65+ years
- Substances:Azd7798
- Sponsor:AstraZeneca AB
Rare diseases
Investigational molecules
Locations
Clinical trials in Germany – page 3043 649 clinical trials in Germany across 214 research sites in 516 cities. Every trial is listed in the EU Clinical Trials Register and updated daily.
Our site in GermanyKlinischeStudien.de(opens in a new tab)
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GermanyWhere most of the country's trials are run
Shares are of these cities' trials together.
516 cities, A–Z – pick yours to filter the trials
What the registry says about research in the country
Germany is conducting extensive clinical trials in oncology, focusing on a wide range of cancers. Research encompasses non-small cell lung cancer, breast cancer, colorectal cancer, and various hematologic malignancies including acute myeloid leukemia, multiple myeloma, and lymphomas. Many trials evaluate novel immunotherapies, targeted therapies, and combination treatment approaches.
These trials aim to improve survival rates, disease control, and quality of life through innovative therapeutic combinations and personalized medicine approaches.
Significant research is underway in autoimmune diseases and immunological disorders. Trials investigate treatments for rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel diseases, and psoriasis. Studies evaluate biologic therapies, monoclonal antibodies, and novel immunomodulatory agents targeting specific pathways involved in immune dysregulation.
Research focuses on achieving remission, reducing disease activity, and minimizing long-term complications through targeted immunological interventions.
Clinical trials in cardiovascular disease address conditions such as heart failure, myocardial infarction, atrial fibrillation, and atherosclerotic cardiovascular disease. Studies evaluate therapies to improve cardiac function, prevent adverse events, and reduce cardiovascular mortality. Research includes investigations of anticoagulants, lipid-lowering agents, and novel approaches to heart failure management.
These trials seek to enhance patient outcomes through improved risk stratification and therapeutic optimization.
German research centers are investigating treatments for neurological disorders including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and epilepsy. Trials explore disease-modifying therapies, symptomatic treatments, and interventions targeting underlying pathological mechanisms. Studies also address rare neurological conditions and neuromuscular disorders.
Research aims to slow disease progression, improve neurological function, and enhance quality of life for patients with chronic neurological conditions.
Trials in respiratory diseases focus on asthma, chronic obstructive pulmonary disease, cystic fibrosis, and interstitial lung diseases. Research evaluates bronchodilators, anti-inflammatory agents, and biologics targeting specific inflammatory pathways. Studies also investigate treatments for pulmonary fibrosis and pulmonary hypertension.
These studies aim to improve lung function, reduce exacerbations, and slow disease progression in patients with chronic respiratory conditions.
Clinical research addresses diabetes mellitus, obesity, metabolic syndrome, and various endocrine disorders. Trials investigate glucose-lowering therapies, weight management interventions, and treatments for conditions such as thyroid disorders and growth hormone deficiency. Studies also evaluate therapies for rare metabolic diseases.
Research focuses on improving metabolic control, preventing complications, and addressing the growing burden of metabolic diseases.
Trials investigate treatments for chronic kidney disease, glomerular diseases, and kidney transplant rejection. Research includes studies on IgA nephropathy, focal segmental glomerulosclerosis, and diabetic kidney disease. Investigations evaluate therapies to slow progression, reduce proteinuria, and preserve renal function.
These trials aim to improve kidney outcomes and reduce the need for renal replacement therapy through targeted interventions.
Germany participates in trials for numerous rare diseases and genetic disorders. Research encompasses conditions such as muscular dystrophies, lysosomal storage diseases, hemophilia, and various inherited metabolic disorders. Studies evaluate gene therapies, enzyme replacement therapies, and novel therapeutic approaches for these conditions.
Research aims to address unmet medical needs in rare disease populations through innovative therapeutic strategies and personalized medicine.
Clinical trials in ophthalmology address conditions such as age-related macular degeneration, diabetic retinopathy, glaucoma, and rare inherited retinal diseases. Studies evaluate anti-VEGF therapies, gene therapies, and novel treatments to preserve vision and slow disease progression.
Research focuses on preventing vision loss and improving visual outcomes through targeted therapeutic interventions.
Trials investigate treatments for atopic dermatitis, psoriasis, hidradenitis suppurativa, and other chronic skin conditions. Research evaluates topical therapies, systemic immunomodulators, and biologic agents targeting inflammatory pathways. Studies also address rare dermatologic conditions and skin cancers.
These trials aim to achieve disease control, reduce symptoms, and improve quality of life for patients with chronic dermatologic conditions.
Research in infectious diseases includes trials on viral infections, bacterial infections, and fungal diseases. Studies evaluate antiviral therapies, antibiotics, and vaccines for conditions such as COVID-19, influenza, hepatitis, and HIV. Research also addresses antimicrobial resistance and prevention strategies.
These trials seek to improve treatment outcomes, prevent transmission, and address emerging infectious disease threats.
Clinical trials address gastrointestinal disorders and liver diseases including inflammatory bowel disease, non-alcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma. Studies evaluate therapies to reduce inflammation, prevent disease progression, and manage complications such as portal hypertension and hepatic encephalopathy.
Research aims to improve disease management, prevent complications, and enhance liver function through targeted interventions.
Germany conducts trials specifically focused on pediatric populations, addressing conditions such as childhood cancers, genetic disorders, autoimmune diseases, and developmental disorders. Research evaluates age-appropriate formulations, dosing strategies, and long-term safety of therapies in children and adolescents.
These studies aim to optimize treatment approaches for young patients while considering growth, development, and long-term outcomes.
Trials investigate treatments for chronic pain conditions, neuropathic pain, and neuromuscular diseases. Research evaluates analgesics, nerve-targeting therapies, and interventions for conditions such as diabetic neuropathy, myasthenia gravis, and various muscular dystrophies.
Research focuses on improving pain control, muscle function, and quality of life for patients with chronic neuromuscular conditions.
Clinical trials address solid organ transplantation, stem cell transplantation, and regenerative therapies. Research evaluates immunosuppressive regimens, prevention of graft rejection, and management of graft-versus-host disease. Studies also investigate novel approaches to improve transplant outcomes and reduce complications.
These trials aim to enhance transplant success rates, minimize immunosuppression-related complications, and improve long-term graft survival.
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