Rare diseases
Investigational molecules
Locations
Clinical trials in Spain – page 1704 446 clinical trials in Spain across 172 research sites in 218 cities. Every trial is listed in the EU Clinical Trials Register and updated daily.
Our site in SpainEnsayosClinicos.es(opens in a new tab)Oral Semaglutide in People With Mild Cognitive Impairment or Mild Dementia of the Alzheimer’s Type
SpainPhase 3 study of ianalumab plus standard drug combination in adults and adolescents with systemic lupus erythematosus
SpainORKA-001 in Patients with Moderate-to-Severe Plaque Psoriasis
SpainEfficacy and Safety of MET097 Once Weekly in People with Overweight or Obesity and Type 2 Diabetes
SpainA study to evaluate the efficacy and safety of MET097 in people with obesity or overweight.
SpainA study to evaluate the effect of olpasiran on major cardiovascular events in patients with atherosclerotic cardiovascular disease and high levels of lipoprotein(a)
SpainEfficacy and Safety Evaluation of Dazodalibep in Patients with Moderate-to-Severe Systemic Sjögren’s Syndrome: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
SpainEvaluation of Dazodalibep Efficacy and Safety in Patients with Moderate-to-Severe Sjögren’s Syndrome: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
SpainA Study Testing How Well BAY 3401016 Works and How Safe It Is in Adults Aged 18 to 45 Years with Alport Syndrome
SpainA study testing cagrilintide and semaglutide for heart safety in people with cardiovascular disease
SpainA study testing cagrilintide and semaglutide combination for kidney damage in people with chronic kidney disease and type 2 diabetes who are overweight or obese
SpainTesting Drug Combinations with GSK4381562A, GSK6097608, GSK4428859 and Dostarlimab in Patients with PD-L1 Positive Head and Neck Cancer That Has Spread or Returned
SpainWhere most of the country's trials are run
Shares are of these cities' trials together.
218 cities, A–Z – pick yours to filter the trials
What the registry says about research in the country
Spain is conducting extensive research in oncology, focusing on various solid tumors and hematological malignancies. Clinical trials are investigating treatments for non-small cell lung cancer (NSCLC), breast cancer, colorectal cancer, melanoma, prostate cancer, and ovarian cancer. Studies are evaluating novel therapies including immunotherapies, targeted therapies, antibody-drug conjugates, and CAR-T cell therapies.
Research emphasizes precision medicine approaches, biomarker-driven patient selection, and improving outcomes in both treatment-naïve and previously treated populations across multiple cancer types.
Clinical trials in Spain are addressing a broad spectrum of autoimmune diseases and immune-mediated conditions. Research focuses on rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease (including Crohn's disease and ulcerative colitis), psoriasis, and psoriatic arthritis. Studies are evaluating biologics, small molecules, and novel immunomodulatory agents.
The research aims to achieve disease remission, improve quality of life, and identify biomarkers for treatment response in patients with moderate to severe autoimmune conditions.
Spain is actively involved in trials for neurodegenerative diseases and neurological disorders. Major focus areas include Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis (ALS), and epilepsy. Studies are investigating disease-modifying therapies, symptomatic treatments, and novel approaches to slow disease progression.
Research emphasizes early intervention strategies, biomarker development, and improving cognitive and motor function in patients with progressive neurological conditions.
Clinical trials are investigating treatments for cardiovascular diseases and metabolic disorders. Key areas include heart failure, atherosclerotic cardiovascular disease, atrial fibrillation, type 2 diabetes, obesity, and dyslipidemia. Studies evaluate novel therapeutics aimed at reducing cardiovascular events and improving metabolic control.
Research focuses on preventing major adverse cardiovascular events, improving glycemic control, and addressing the interconnected nature of cardiovascular and metabolic diseases.
Spain conducts trials for respiratory conditions including asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis, and pulmonary arterial hypertension. Studies are evaluating biologics, bronchodilators, and antifibrotic agents to improve lung function and reduce exacerbations.
The research aims to enhance respiratory function, reduce disease progression, and improve quality of life in patients with chronic and progressive lung diseases.
Clinical trials in Spain address infectious diseases including COVID-19, HIV, hepatitis, influenza, and bacterial infections. Research focuses on developing vaccines, antiviral therapies, antibiotics for resistant pathogens, and preventive strategies for high-risk populations.
Studies aim to improve infection prevention, develop effective treatments for resistant pathogens, and address emerging infectious disease challenges.
Spain participates in trials for rare diseases and genetic disorders. Research includes lysosomal storage diseases, muscular dystrophies, hemophilia, spinal muscular atrophy, and metabolic disorders. Studies evaluate gene therapies, enzyme replacement therapies, and novel targeted treatments.
Research focuses on addressing unmet medical needs in rare disease populations through innovative therapeutic approaches and improving patient outcomes.
Clinical trials are investigating treatments for kidney diseases including chronic kidney disease (CKD), IgA nephropathy, focal segmental glomerulosclerosis, and kidney transplant rejection. Studies evaluate therapies to slow disease progression, reduce proteinuria, and improve transplant outcomes.
Research aims to reduce progression to end-stage renal disease, improve kidney transplant success, and enhance quality of life for patients with chronic kidney conditions.
Spain conducts research on hematological disorders including anemia, thrombocytopenia, hemophilia, sickle cell disease, and myelodysplastic syndromes. Studies are evaluating novel therapies to improve blood cell production, prevent bleeding, and manage clotting disorders.
The research focuses on reducing transfusion dependence, preventing bleeding complications, and improving outcomes in patients with inherited and acquired blood disorders.
Clinical trials in Spain address dermatological conditions including atopic dermatitis, psoriasis, hidradenitis suppurativa, vitiligo, and alopecia areata. Research evaluates biologics, topical therapies, and systemic treatments to improve skin health and quality of life.
Studies aim to achieve disease clearance, reduce symptoms, and improve patient quality of life in chronic and debilitating skin conditions.
Spain participates in trials for eye diseases including age-related macular degeneration, diabetic retinopathy, glaucoma, and retinal vein occlusion. Research focuses on anti-VEGF therapies, gene therapies, and novel treatments to preserve vision and prevent blindness.
The research aims to improve visual outcomes, reduce treatment burden, and address unmet needs in patients with progressive retinal and optic nerve diseases.
Clinical trials are investigating treatments for gastrointestinal and liver diseases including non-alcoholic steatohepatitis (NASH), cirrhosis, primary biliary cholangitis, and eosinophilic esophagitis. Studies evaluate antifibrotic agents, immunomodulators, and metabolic therapies.
Research focuses on slowing disease progression, preventing liver-related complications, and improving outcomes in patients with chronic liver and gastrointestinal conditions.
Spain conducts trials for pain management and anesthesia. Research includes chronic pain, neuropathic pain, postoperative pain, and migraine. Studies evaluate analgesics, nerve blocks, and novel pain modulation techniques.
The research aims to improve pain control, reduce opioid use, and enhance recovery in patients undergoing surgery or living with chronic pain conditions.
Clinical trials in Spain address organ transplantation and regenerative therapies. Research focuses on kidney transplant, liver transplant, lung transplant, and hematopoietic stem cell transplantation. Studies evaluate immunosuppressive regimens, rejection prevention, and cell-based therapies.
Research aims to enhance transplant success rates, reduce rejection episodes, and improve long-term graft survival in solid organ and stem cell transplant recipients.
Spain participates in trials for pediatric conditions across multiple therapeutic areas. Research includes pediatric cancers, genetic disorders, inflammatory diseases, and rare pediatric conditions. Studies evaluate age-appropriate formulations, dosing regimens, and safety profiles in children.
The research focuses on developing safe and effective treatments tailored to pediatric populations, addressing unique challenges in children with serious and rare diseases.
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