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Find clinical trials for children in your area – page 27

recruiting
312
countries
27
conditions
393

755 paediatric trials match your criteria

Dermatitis atopic

Not yet recruiting

Study on Rocatinlimab for Adolescents Aged 12-17 with Moderate-to-Severe Atopic Dermatitis

InvestigationalNo placebo
Countries:AustriaAustria
  • Participants:0–17 years
  • Substances:Rocatinlimab

Long‑Term Safety and Tolerability of Oral Iptacopan in Pediatric Patients with Paroxysmal Nocturnal Hemoglobinuria or IgA Nephropathy

InvestigationalNo placebo
Countries:ItalyItaly
  • Participants:0–17 years
  • Substances:Iptacopan

Neoplasm

Not yet recruiting

Phase 2 Study Evaluating Safety and Efficacy of Belzutifan in Adults with Solid Tumors

InvestigationalNo placebo
Countries:BelgiumBelgium
  • Participants:0–17 years
  • Substances:Belzutifan

Safety, Tolerability and Immunogenicity of RSV prefusion F protein 847a and 847b Vaccine in Children 5‑17 Years at High Risk of RSV Disease

Registered drug
Countries:PolandPoland
  • Participants:0–17 years

Pneumococcal immunisation

Not yet recruiting

Safety and immune response of PF-07872412 compared with 20-valent pneumococcal conjugate vaccine for pneumococcal disease in healthy children and adolescents

Registered drugNo placebo
Countries:FinlandFinland
  • Participants:0–17 years
  • Substances:Pneumococcal Polysaccharide Serotype 1 Conjugated To Crm197 Adsorbed On Aluminium Phosphate

Type 2 diabetes mellitus

Not yet recruiting

Phase 3 Study of Oral Orforglipron vs Weekly Dulaglutide in Children and Adolescents (10‑<18 years) with Type 2 Diabetes

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:0–17 years
  • Substances:Dulaglutide

Study of subcutaneous anifrolumab pharmacokinetics, pharmacodynamics and safety in children aged 5 to <18 years with systemic lupus erythematosus

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:0–17 years
  • Substances:Anifrolumab

Sickle cell disease

Not yet recruiting

A study of etavopivat to reduce vaso‑occlusive crises in children with sickle cell disease

Investigational
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Etavopivat

Varicella+5

Not yet recruiting

Immune response and safety of investigational MMRV vaccine (GSKVX000000025896) drug combination compared with standard MMRV vaccine in healthy children 15 months to 6 years

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years · Healthy volunteers
  • Substances:GSKVX000000025896

Effect of Methylphenidate versus Placebo on Attachment‑Related Learning in Children with Attention‑Deficit/Hyperactivity Disorder (ADHD)

Registered drug
Countries:BelgiumBelgium
  • Participants:0–17 years
  • Substances:Methylphenidate Hydrochloride

Epilepsy

Not yet recruiting

Efficacy of fluoxetine added to standard anti‑seizure therapy in children aged 8 years and older with drug‑resistant complex and rare epilepsy

Registered drug
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Fluoxetine

Gaucher's disease type III

Not yet recruiting

Efficacy and safety of oral venglustat versus intravenous imiglucerase in children aged 2‑11 years with Gaucher disease type 3

Registered drugNo placebo
Countries:FinlandFinland
  • Participants:0–17 years
  • Substances:Imiglucerase

About paediatric clinical trials

Pediatric Clinical Trials: Research Opportunities for Children and Adolescents

Clinical research plays a vital role in developing safe and effective treatments for younger patients. Pediatric clinical trials are trials designed specifically for infants, children, and adolescents. They help researchers understand how new therapies, vaccines, or medical procedures work in younger populations and ensure that treatments are safe and appropriate for their age group.

Why Pediatric Clinical Trials Are Important

Children are not simply smaller versions of adults. Their bodies grow and develop, which means medications may work differently than they do in adults. For this reason, therapies must be carefully studied in pediatric populations.

Another important reason for pediatric clinical trials is that some diseases occur primarily or exclusively in children. Certain genetic conditions, developmental disorders, and rare pediatric diseases affect only young patients. Without dedicated research involving children and adolescents, it would be difficult to develop treatments specifically designed for these conditions.

Pediatric research also helps doctors determine:

  • the correct dosage of medications for children of different ages
  • how developing organs respond to treatments
  • whether therapies are safe and effective in younger patients
  • how treatments affect long-term growth and development

Who Can Participate in Pediatric Clinical Trials

Participants in pediatric clinical trials may include infants, children, and teenagers depending on the trial design. Each trial has specific eligibility criteria based on age, health condition, and medical history.

Because participants are minors, the process always involves:

  • Informed consent from parents or legal guardians
  • Age-appropriate explanation of the trial to the child
  • In many cases, assent from the child or adolescent confirming they agree to participate

This ensures that families fully understand the purpose of the research, the procedures involved, and any potential risks or benefits.

Safety and Ethical Oversight

Safety is the highest priority in pediatric clinical trials. These trials follow strict ethical and regulatory standards in Europe and internationally. Research protocols are reviewed by ethics committees and regulatory authorities to ensure that the risks are minimized and justified by the potential benefits of the research.

Children participating in clinical trials are monitored closely by qualified healthcare professionals throughout the entire process. Families receive detailed information about trial procedures, medical monitoring, and the right to withdraw from the trial at any time.

How Families Can Find Pediatric Clinical Trials

Our search platform allows parents and guardians to explore pediatric clinical trials available in different regions. Using the search tool, families can find trials based on factors such as age group, medical condition, and location.

Clinical trials for children and adolescents are essential for advancing pediatric medicine. By participating in research, families contribute to the development of safer and more effective treatments for young patients today and in the future.

Clinical Trials Concierge

Prefer not to search? Our Concierge searches the trials for you.

Tell us about your condition – we search every trial in Europe and connect you with the right site.