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Clinical Trials – home

Find clinical trials for children in your area – page 45

recruiting
312
countries
27
conditions
393

755 paediatric trials match your criteria

Erdheim-Chester disease+3

Not recruiting

Study on Vemurafenib for Children with BRAF Mutation-Resistant Histiocytosis

Registered drugNo placebo
Countries:PolandPoland
  • Participants:0–17 years
  • Substances:Vemurafenib

Study on the Long-Term Safety of Pimavanserin for Treating Irritability in Children and Adolescents with Autism Spectrum Disorder

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Pimavanserin Tartrate

Study on the Safety and Efficacy of Delandistrogene Moxeparvovec and Imlifidase for Patients with Duchenne Muscular Dystrophy with Pre-existing Antibodies

Registered drugNo placebo
Countries:SpainSpain
  • Participants:0–17 years
  • Substances:Imlifidase

Cystic fibrosis

Not recruiting

Study on Long-term Safety and Efficacy of Elexacaftor, Tezacaftor, and Ivacaftor in Children and Adults with Cystic Fibrosis Aged 2 Years and Older

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years
  • Substances:Elexacaftor

Myopia

Not recruiting

Study on Atropine Sulfate Eye Drops to Slow Down Myopia in European Children

Investigational
Countries:GermanyGermany
  • Participants:0–17 years
  • Substances:Atropine Sulfate

Study on the Long-Term Safety of Nintedanib for Children and Adolescents with Interstitial Lung Disease

InvestigationalNo placebo
Countries:BelgiumBelgium
  • Participants:0–17 years
  • Substances:Nintedanib

Dermatitis atopic

Not recruiting

Study on Tralokinumab for Children Aged 6-11 with Moderate-to-Severe Atopic Dermatitis

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:0–17 years
  • Substances:Tralokinumab

Study on ECUR-506A and ECUR-506D for Male Infants Under 9 Months with Neonatal Onset Ornithine Transcarbamylase Deficiency

InvestigationalNo placebo
Countries:SpainSpain
  • Participants:0–17 years
  • Substances:Adeno-Associated Virus Serotype Rh79 Containing The Human Otc Gene

Obesity

Not recruiting

Study of Tirzepatide for Reducing Obesity and Related Health Issues in Adolescents

Investigational
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Tirzepatide

Ventricular drainage

Not recruiting

Study on How Antibiotics Work in the Spinal Fluid of Children with Brain Drains: Cefuroxime, Vancomycin, and Gentamicin with a Drug Combination

Registered drugNo placebo
Countries:AustriaAustria
  • Participants:0–17 years
  • Substances:Ampicillin Sodium

Study on the Effects of Satralizumab in Children and Adolescents with Duchenne Muscular Dystrophy

InvestigationalNo placebo
Countries:DenmarkDenmark
  • Participants:0–17 years

Study on the Safety and Effects of Regadenoson and Gadobutrol in Heart Imaging for Children with Cardiovascular Conditions

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Gadobutrol

About paediatric clinical trials

Pediatric Clinical Trials: Research Opportunities for Children and Adolescents

Clinical research plays a vital role in developing safe and effective treatments for younger patients. Pediatric clinical trials are trials designed specifically for infants, children, and adolescents. They help researchers understand how new therapies, vaccines, or medical procedures work in younger populations and ensure that treatments are safe and appropriate for their age group.

Why Pediatric Clinical Trials Are Important

Children are not simply smaller versions of adults. Their bodies grow and develop, which means medications may work differently than they do in adults. For this reason, therapies must be carefully studied in pediatric populations.

Another important reason for pediatric clinical trials is that some diseases occur primarily or exclusively in children. Certain genetic conditions, developmental disorders, and rare pediatric diseases affect only young patients. Without dedicated research involving children and adolescents, it would be difficult to develop treatments specifically designed for these conditions.

Pediatric research also helps doctors determine:

  • the correct dosage of medications for children of different ages
  • how developing organs respond to treatments
  • whether therapies are safe and effective in younger patients
  • how treatments affect long-term growth and development

Who Can Participate in Pediatric Clinical Trials

Participants in pediatric clinical trials may include infants, children, and teenagers depending on the trial design. Each trial has specific eligibility criteria based on age, health condition, and medical history.

Because participants are minors, the process always involves:

  • Informed consent from parents or legal guardians
  • Age-appropriate explanation of the trial to the child
  • In many cases, assent from the child or adolescent confirming they agree to participate

This ensures that families fully understand the purpose of the research, the procedures involved, and any potential risks or benefits.

Safety and Ethical Oversight

Safety is the highest priority in pediatric clinical trials. These trials follow strict ethical and regulatory standards in Europe and internationally. Research protocols are reviewed by ethics committees and regulatory authorities to ensure that the risks are minimized and justified by the potential benefits of the research.

Children participating in clinical trials are monitored closely by qualified healthcare professionals throughout the entire process. Families receive detailed information about trial procedures, medical monitoring, and the right to withdraw from the trial at any time.

How Families Can Find Pediatric Clinical Trials

Our search platform allows parents and guardians to explore pediatric clinical trials available in different regions. Using the search tool, families can find trials based on factors such as age group, medical condition, and location.

Clinical trials for children and adolescents are essential for advancing pediatric medicine. By participating in research, families contribute to the development of safer and more effective treatments for young patients today and in the future.

Clinical Trials Concierge

Prefer not to search? Our Concierge searches the trials for you.

Tell us about your condition – we search every trial in Europe and connect you with the right site.