Azienda Ospedaliero-Universitaria Maggiore Della Carita

At Azienda Ospedaliero-Universitaria Maggiore Della Carita, the Department of Neurology and ALS Center support studies focused on nervous system diseases and related quality-of-life outcomes. Research includes major conditions such as Amyotrophic Lateral Sclerosis, Alzheimer’s disease, and Parkinson’s disease, with trials aimed at testing new symptom-relief approaches and improving daily functioning.

• Neurodegenerative disease management, including ALS, Alzheimer’s disease, and Parkinson’s disease
• Evaluation of treatments designed to improve quality of life and patient comfort
• Supportive care research in a specialist neurology setting

The site’s neurology expertise also connects with broader work on neurological complications and brain-related outcomes, reflecting a strong focus on practical, patient-centered care.

This research program includes several trials in hemic and lymphatic diseases, especially follicular lymphoma, marginal zone lymphoma, diffuse large B-cell lymphoma, chronic lymphocytic leukemia, and multiple myeloma. The studies are designed to compare new immunotherapies and targeted treatments with current standards of care, with the goal of improving disease control and response rates.

• Relapsed or refractory follicular lymphoma and marginal zone lymphoma
• Newly diagnosed and previously treated aggressive B-cell lymphoma
• Multiple myeloma and chronic lymphocytic leukemia treatment strategies

These trials show a strong interest in advancing blood cancer care through more effective and better-tolerated therapies.

The site is active in neoplasms, with studies in early breast cancer, advanced breast cancer, non-small cell lung cancer, head and neck squamous cell carcinoma, and prostate cancer. Research here often aims to determine whether newer hormone-based, immune-based, or targeted approaches can improve progression-free survival and reduce recurrence.

• ER-positive, HER2-negative breast cancer in early and advanced settings
• Non-small cell lung cancer with specific molecular features
• Prostate cancer and head and neck cancer treatment optimization

These oncology studies reflect a broad effort to refine treatment effectiveness across both common and more specialized cancer types.

Clinical trials at this center also cover nutritional and metabolic diseases, digestive system diseases, and cardiovascular diseases. Key conditions include obesity, type 2 diabetes, MASH, NASH, heart failure, and atrial fibrillation, with studies focused on improving long-term risk reduction, liver health, and cardiometabolic outcomes.

• Obesity, overweight, and type 2 diabetes management
• Liver disease research in NASH and MASH with fibrosis
• Heart failure and stroke prevention in cardiovascular disease

These trials combine prevention and treatment goals, aiming to better control chronic disease progression and associated complications.

The site also conducts studies in immune system diseases and related inflammatory conditions, including lupus nephritis, autoimmune disease, fibrosis, and chronic kidney disease. The main purpose of this research is to evaluate whether targeted therapies can reduce inflammation, protect organ function, and improve clinical outcomes.

• Lupus nephritis and other immune-mediated kidney conditions
• Autoimmune and inflammatory disease treatment evaluation
• Fibrosis-related disease progression and organ protection

These investigations add an important translational dimension to the Novara research portfolio, linking immune control with better long-term health outcomes.

In addition to specialty disease areas, the research portfolio includes eye diseases such as glaucoma, as well as studies with environment and public health relevance. These trials aim to improve visual preservation, support safer care strategies, and evaluate therapies that may have broader quality-of-life benefits.

• Glaucoma research focused on preserving vision
• Public health-oriented clinical studies with patient-centered outcomes
• Supportive care approaches that may improve everyday functioning

Across these areas, the site combines focused specialty care with broader efforts to improve outcomes that matter to patients in daily life.