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Goethe University Frankfurt

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Germany Theodor-Stern-Kai 7, Sachsenhausen, 60596 Frankfurt, Germany

  • 256 trials recruiting
  • Acute myeloid leukaemia · Non-small cell lung cancer · Dermatitis atopic
  • Adults and children

About Specializations

Goethe University Frankfurt in Frankfurt, Germany specialises in clinical trials of conditions such as Acute myeloid leukaemia, Non-small cell lung cancer, Dermatitis atopic, Acute lymphocytic leukaemia, and other specialisations. This site conducts important research.

Main research areas of the site

TSC‑Related Epilepsy Research

At the Epilepsy Center Frankfurt Rhine-Main, investigators are focusing on Tuberous Sclerosis Complex–related seizures, exploring new options to improve long‑term control for both children and adults.

  • Long‑term safety and tolerability evaluation
  • Adjunctive therapy with Ganaxolone
  • Inclusion of pediatric and adult populations
  • Monitoring of seizure frequency and quality of life

The program underscores Goethe University Frankfurt’s commitment to advancing treatments for nervous system disorders.

Targeted Therapy for H3 K27M‑Mutant Diffuse Glioma

Researchers are evaluating a precision approach for patients with H3 K27M‑mutant diffuse glioma, aiming to enhance outcomes after standard radiotherapy.

  • Molecularly driven drug assessment
  • Post‑radiation maintenance strategy
  • Exploration of survival benefit
  • Integration of biomarker analysis

The study highlights the site’s expertise in neuro‑oncology within the broader neoplasm therapeutic area.

Vaccination Approach for Recurrent Glioblastoma and Astrocytoma

A novel immunotherapy trial is testing the CVGBM vaccine in patients who have undergone surgery for glioblastoma or astrocytoma, seeking to prevent tumor recurrence.

  • Dose‑escalation safety assessment
  • Evaluation of immune response activation
  • Post‑surgical adjuvant treatment model
  • Comprehensive adverse‑event monitoring

This effort reflects the center’s dedication to innovative cancer therapies within the neoplasms research portfolio.

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Site location
Theodor-Stern-Kai 7, Sachsenhausen60596 FrankfurtGermany
Recruiting now
256 trials
Conditions studied
253
Partner status
Verified

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Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

611 clinical trials

Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Golimumab
  • Sponsor:Janssen Cilag International
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:SPY002
  • Sponsor:Spyre Therapeutics Inc.
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Topotecan Hydrochloride
  • Sponsor:Zai Lab (US) LLC
Countries:GermanyGermany
  • Participants:0–17 years
  • Substances:Lebrikizumab
  • Sponsor:Eli Lilly & Co.
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Sponsor:Novo Nordisk A/S
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Lebrikizumab
  • Sponsor:Almirall S.A.
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:BI 456906
  • Sponsor:Boehringer Ingelheim International GmbH
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:BI 456906
  • Sponsor:Boehringer Ingelheim International GmbH
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:BioNTech SE
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:MOLNUPIRAVIR
  • Sponsor:Merck Sharp & Dohme LLC
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Deucravacitinib
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:SPY002
  • Sponsor:Spyre Therapeutics Inc.
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