Radboudumc

Research at Radboudumc focuses on nervous system diseases, with studies centered on movement-related conditions such as dystonic tremor syndrome and Parkinson's disease. The trials aim to better understand symptoms and evaluate whether targeted treatments can improve tremor control and gait-related problems.

• Exploring factors linked to botulinum neurotoxin effectiveness for arm tremor in dystonia
• Studying treatment approaches for freezing of gait in Parkinson's disease

This work combines clinical observation with brain-based research to support more personalized care for people living with movement disorders.

The site also investigates behavior and behavior mechanisms, including how brain chemistry influences learning and decision-making. These studies are designed to improve understanding of how serotonin affects everyday cognitive processes and behavior.

• Examining the role of serotonin in learning
• Assessing how neurochemical pathways shape decision-making

By linking biology with behavior, this research may help clarify why some people respond differently to cognitive and emotional challenges.

Clinical research in mental disorders includes studies in posttraumatic stress disorder, with a strong interest in stress regulation and personalized treatment. The trials are looking at how early life experiences and hormone-related systems may influence recovery and response to therapy.

• Investigating links between early life adversity, epigenetic changes, and stress-system dysregulation in PTSD
• Evaluating whether hydrocortisone support can strengthen safety learning in selected patients

At Radboudumc, this line of research aims to improve both the understanding and treatment of trauma-related conditions.