Clinical trials in Zwolle – page 13

197 clinical trials in Zwolle, The Netherlands across 4 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Zwolle at a glance

197

clinical trials

Research sites4

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197 trials in Zwolle

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B precursor type acute leukaemia

Not recruiting

Study on Adding Blinatumomab to Treatment for Adults with Precursor B-Acute Lymphoblastic Leukemia

Registered drugNo placebo

Study on Adding Blinatumomab to Treatment for Adults with Precursor B-Acute Lymphoblastic Leukemia

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Blinatumomab
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

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Hormone receptor positive HER2 negative breast cancer

Not recruiting

Study Comparing Two Treatment Sequences of CDK4/6 Inhibitors (Abemaciclib, Palbociclib, or Ribociclib) in Hormone Receptor Positive Advanced Breast Cancer

Registered drugNo placebo

Study Comparing Two Treatment Sequences of CDK4/6 Inhibitors (Abemaciclib, Palbociclib, or Ribociclib) in Hormone Receptor Positive Advanced Breast Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Abemaciclib
Sponsor:BOOG Study Center B.V.

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Breast cancer stage III+2

Not recruiting

Study of Trastuzumab, Pertuzumab, and Chemotherapy Combination with Response-Guided Treatment for Patients with HER2-Positive Breast Cancer

Registered drugNo placebo

Study of Trastuzumab, Pertuzumab, and Chemotherapy Combination with Response-Guided Treatment for Patients with HER2-Positive Breast Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:BOOG Study Center B.V.

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Colorectal cancer

Not recruiting

Study of organ preservation using chemoradiotherapy and transanal surgery compared to standard surgery in patients with early rectal cancer (STAR-TREC trial)

Registered drugNo placebo

Study of organ preservation using chemoradiotherapy and transanal surgery compared to standard surgery in patients with early rectal cancer (STAR-TREC trial)

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Capecitabine
Sponsor:The University Of Birmingham

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Diffuse large B-cell lymphoma+1

Not recruiting

Study of Brentuximab Vedotin Combined with R-DHAP Chemotherapy for Patients with Relapsed or Treatment-Resistant CD30-Positive Diffuse Large B-Cell Lymphoma Who Are Eligible for Stem Cell Transplant

Registered drugNo placebo

Study of Brentuximab Vedotin Combined with R-DHAP Chemotherapy for Patients with Relapsed or Treatment-Resistant CD30-Positive Diffuse Large B-Cell Lymphoma Who Are Eligible for Stem Cell Transplant

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Brentuximab Vedotin
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

Contact Research Centre

Chronic kidney disease

Not recruiting

Study on Dapagliflozin for Patients with Severe Chronic Kidney Disease to Improve Kidney and Heart Health Outcomes

Registered drug

Study on Dapagliflozin for Patients with Severe Chronic Kidney Disease to Improve Kidney and Heart Health Outcomes

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Dapagliflozin
Sponsor:Universitair Medisch Centrum Groningen

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Non-small cell lung cancer+2

Not recruiting

Study of Niraparib and Pembrolizumab for Patients with Advanced Non-Small Cell Lung Cancer

Registered drug

Study of Niraparib and Pembrolizumab for Patients with Advanced Non-Small Cell Lung Cancer

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Pembrolizumab
Sponsor:Glaxosmithkline Research & Development Limited

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Plasma cell myeloma

Not recruiting

Study Comparing Talquetamab, Pomalidomide, and Teclistamab for Patients with Relapsed or Refractory Myeloma After 1 to 4 Prior Treatments

Registered drugNo placebo

Study Comparing Talquetamab, Pomalidomide, and Teclistamab for Patients with Relapsed or Refractory Myeloma After 1 to 4 Prior Treatments

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Bortezomib
Sponsor:Janssen Cilag International

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Severe myoclonic epilepsy of infancy+1

Not recruiting

Study on Long-Term Safety of Soticlestat for Patients with Dravet or Lennox-Gastaut Syndromes

InvestigationalNo placebo

Study on Long-Term Safety of Soticlestat for Patients with Dravet or Lennox-Gastaut Syndromes

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Soticlestat
Sponsor:Takeda Development Center Americas Inc.

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Dementia Alzheimer's type

Not recruiting

Study on the Effectiveness and Safety of GSK4527226 in Patients with Early Alzheimer's Disease

Registered drug

Study on the Effectiveness and Safety of GSK4527226 in Patients with Early Alzheimer's Disease

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Florbetaben (18F)
Sponsor:Glaxosmithkline Research & Development Limited

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Non-small cell lung cancer stage III+5

Not recruiting

Study Comparing Ociperlimab and Tislelizumab with Pembrolizumab for Patients with Advanced Non-Small Cell Lung Cancer

Registered drug

Study Comparing Ociperlimab and Tislelizumab with Pembrolizumab for Patients with Advanced Non-Small Cell Lung Cancer

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ociperlimab
Sponsor:Beigene Ltd.

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Migraine

Not recruiting

Study on Lasmiditan for Treating Migraine in Children Aged 6 to 17

Registered drug

Study on Lasmiditan for Treating Migraine in Children Aged 6 to 17

Registered drug

The Netherlands

Participants:0–17 years
Substances:Lasmiditan
Sponsor:Eli Lilly & Co.

Contact Research Centre

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Clinical research in Zwolle

What the registry says about research in the country

01 Oncology Research

Innovative clinical trials exploring treatments for colorectal cancer, non-small cell lung cancer, and acute myeloid leukemia. Studies focus on evaluating novel drug combinations and targeted therapies to improve patient outcomes.

Advanced cancer treatments
Targeted therapy combinations
Immunotherapy research

Several trials investigating new approaches for melanoma and prostate cancer management.

02 Cardiovascular Studies

Research focusing on heart failure prevention and cardiovascular disease management. Trials evaluating new drug combinations including baxdrostat and dapagliflozin for improved cardiac outcomes.

Heart failure prevention
Cardiovascular risk reduction
Novel therapeutic approaches

Emphasis on preventive strategies and innovative treatment combinations.

03 Neurological Disorders

Clinical investigations into narcolepsy and Alzheimer's disease treatments. Studies evaluating new therapeutic options for Dravet Syndrome and various neurological conditions.

Sleep disorders
Cognitive function
Seizure management

Focus on improving quality of life and symptom management for patients.

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