Centre Hospitalier Universitaire d’Orléans

This site is conducting clinical research in virus diseases, with a focus on HIV-1 infection. The studies are designed to explore better ways to control the virus and support long-term treatment success in adults living with HIV.

• Evaluating the effectiveness of new antiretroviral therapy approaches for people starting HIV treatment
• Assessing whether treatment can maintain viral suppression over time with simpler care options
• Comparing patient-centered treatment strategies for improved convenience and adherence

The research in this area aims to improve both treatment effectiveness and the overall experience of care for HIV patients.

Clinical trials in digestive system diseases at the Hépato-Gastroentérologie department are centered on primary biliary cholangitis in patients who do not respond well enough to standard therapy. These studies are looking at whether additional treatment options can improve disease control.

• Testing adjunctive treatments for patients with a non-optimal response to ursodeoxycholic acid
• Studying ways to improve biochemical response in primary biliary cholangitis
• Comparing new supportive strategies against placebo to assess treatment benefit

The goal is to refine care for chronic liver-related conditions and identify options that may offer better disease management for people with PBC.